Polymeric micelles are nanocarriers that water-solubilize hydrophobic drug molecules yet can also be bioactive by themselves. These polymers were designed with a branched, hydrophobic interior (core) and hydrophilic exterior (shell) to maintain physical properties characteristic of conventional micelles, but with enhanced thermodynamic stability.
Two general classes of nanoscale polymeric micelles are under investigation: amphiphilic starlike macromolecules (ASMs) and amphiphilic scorpion-like macromolecules (AScMs). These two systems are chemically similar, but structurally different. ASMs behave as unimolecular micelles, whereas AScMs must first aggregate to form micellar structures.
Rutgers new scanning transmission electron microscope and new helium ion microscope help researchers develop nanotechnology used to fight cancer, generate power, and create more powerful electronics. Watch the video to learn more.