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Biotechnology and Biochemical Engineering


Tuesday, October 20, 2015

The Biotechnology and Biochemical Engineering (BBE) program supports fundamental engineering research that advances the understanding of cellular and biomolecular processes in engineering biology and eventually leads to the development of enabling technology for advanced manufacturing and/or applications in support of the biopharmaceutical, biotechnology, and bioenergy industries, or with applications in health or the environment. A quantitative treatment of biological and engineering problems of biological processes is considered vital to successful research projects in the BBE program.

Fundamental to many research projects in this area is the understanding of how biomolecules, cells and cell populations interact in their environment, and how those molecular level interactions lead to changes in structure, function, phenotype, and/or behavior. The program encourages highly innovative and potentially transformative engineering research leading to novel bioprocessing and manufacturing approaches, and proposals that address emerging research areas and technologies that effectively integrate knowledge and practices from different disciplines while incorporating ongoing research into educational activities.

Major areas of interest in the program include:

Metabolic engineering and synthetic biology for biomanufacturing
Quantitative systems biotechnology
Tissue engineering and stem cell culture technologies
Protein engineering & design
Single cell dynamics and modeling
Development of novel "omics" tools for biotechnology applications
NOTE: For proposals involving any aspect of sustainable chemistry and engineering, including but not limited to biochemistry or physical chemistry, consider making proposal submissions to this program (1491) with the Proposal Title as: ‘SusChEM: Title of Your Proposal'. For more information on SusChEM-related proposals click here.

The duration of unsolicited awards is generally one to three years. The typical award size for the program is around $100,000 per year with allowance for up to $200,000 per year for collaborative projects or those involving multiple investigators. Proposals requesting a substantially higher amount than this, without prior consultation with the Program Director, may be returned without review.

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