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Chemical Synthesis


Wednesday, September 30, 2015


Note:  For proposals with significant emphasis on sustainable chemistry, consider making proposal submissions to this program with the Proposal Title as:  ‘SusChEM: Name of Your Proposal'.  For more information, see the DCL on SusChEM (, a new NSF Emphasis Area."   

The Chemical Synthesis program focuses on the development of new, efficient synthetic methodologies and on the synthesis of complex and/or challenging molecules.  Typical synthetic targets involve novel structures, structures displaying unique properties, or structures providing pathways to discover and elucidate new phenomena.  Examples of supported research areas include the development of innovative reagents, catalysts for synthetic transformations, discovery of new synthetic methods, target-oriented synthesis, green synthesis, and synthesis of novel organic, organometallic, and inorganic structures.  Research in this program will generate fundamental knowledge of chemical synthesis that enables the development of new avenues of basic chemical research and transformative technologies. 

Submissions that address national needs for sustainability are encouraged.  Examples include the development of new synthetic methods using earth-abundant and inexpensive chemicals, fundamental studies that improve our understanding of rare earth elements, and the conversion of non-petroleum based resources into useful building blocks.   

The Chemical Synthesis program does not support projects whose main objectives are to study the properties of target systems even though they may contain a large synthetic component.  Synthesis of nano structures, supramolecular assemblies, and polymers should be directed to the Macromolecular, Supramolecular and Nanochemistry program.  Proposals containing a synthesis component but having a major focus on the mechanistic study of catalytic reactions should be submitted to the Chemical Catalysis program. 

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