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Advanced Development and Validation of Emerging Technologies for Cancer-Relevant Biospecimen Science (R33)


Tuesday, September 22, 2015

This Funding Opportunity Announcement (FOA) solicits grant applications proposing research projects on the advanced development and validation of technologies that address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and storage of cancer-relevant biospecimens. Applications must include preliminary data sufficient to justify the feasibility of the proposed technology, but may still require additional development to reach a generally useful level of functionality for cancer-related research applications. The overall goal is to support the development of highly innovative technologies capable of interrogating and/or maximizing the quality and utility of biospecimens or samples derived from those biospecimens for downstream analyses. This FOA will support the development of tools, devices, instrumentation, and associated methods to assess sample quality, preserve/protect sample integrity, and establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to potentially accelerate and/or enhance research in cancer biology, early detection, screening, clinical diagnosis, treatment, epidemiology, and cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.

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